发明名称 |
Halogenated rhodamine derivatives and applications thereof |
摘要 |
Methods for treating an infection in a tissue sample are described. Tissue samples that are harvested from a patient may be infected with either bacteria or a virus. A rhodamine compound is mixed with the infected tissue sample to form a mixture. The mixture is then exposed to radiant energy to inhibit or kill the bacteria. The exposed mixture is then transplanted into the patient. The rhodamine compounds may be 2′-(6-dimethylamino-3-dimethylimino-3H-xanthen-9-yl) 4′, 5′-dichloro-benzoic acid methyl ester hydrochloride. |
申请公布号 |
US9636363(B2) |
申请公布日期 |
2017.05.02 |
申请号 |
US201313752204 |
申请日期 |
2013.01.28 |
申请人 |
Kiadis Pharma Canada Inc. |
发明人 |
Habi Abdelkrim;Gravel Denis;Villeneuve Luc;Su Hongsheng;Vaillancourt Marc |
分类号 |
A61K35/28;C07D311/82;A61K35/14 |
主分类号 |
A61K35/28 |
代理机构 |
O'Melveny & Myers LLP |
代理人 |
O'Melveny & Myers LLP |
主权项 |
1. A method for treating a tissue sample from a patient, comprising the steps of:
harvesting the tissue sample from the patient, wherein the tissue sample is infected with bacteria, wherein the bacteria is gram positive; providing a rhodamine compound, wherein the rhodamine compound is 2′-(6-dimethylamino-3-dimethylimino-3H-xanthen-9-yl) 4′, 5′-dichloro-benzoic acid methyl ester hydrochloride; mixing the rhodamine compound and the tissue sample to form a mixture, exposing the mixture to radiant energy to inhibit or kill the bacteria; and transplanting the exposed mixture into the patient. |
地址 |
Saint Lambert, QC CA |