发明名称 Halogenated rhodamine derivatives and applications thereof
摘要 Methods for treating an infection in a tissue sample are described. Tissue samples that are harvested from a patient may be infected with either bacteria or a virus. A rhodamine compound is mixed with the infected tissue sample to form a mixture. The mixture is then exposed to radiant energy to inhibit or kill the bacteria. The exposed mixture is then transplanted into the patient. The rhodamine compounds may be 2′-(6-dimethylamino-3-dimethylimino-3H-xanthen-9-yl) 4′, 5′-dichloro-benzoic acid methyl ester hydrochloride.
申请公布号 US9636363(B2) 申请公布日期 2017.05.02
申请号 US201313752204 申请日期 2013.01.28
申请人 Kiadis Pharma Canada Inc. 发明人 Habi Abdelkrim;Gravel Denis;Villeneuve Luc;Su Hongsheng;Vaillancourt Marc
分类号 A61K35/28;C07D311/82;A61K35/14 主分类号 A61K35/28
代理机构 O'Melveny & Myers LLP 代理人 O'Melveny & Myers LLP
主权项 1. A method for treating a tissue sample from a patient, comprising the steps of: harvesting the tissue sample from the patient, wherein the tissue sample is infected with bacteria, wherein the bacteria is gram positive; providing a rhodamine compound, wherein the rhodamine compound is 2′-(6-dimethylamino-3-dimethylimino-3H-xanthen-9-yl) 4′, 5′-dichloro-benzoic acid methyl ester hydrochloride; mixing the rhodamine compound and the tissue sample to form a mixture, exposing the mixture to radiant energy to inhibit or kill the bacteria; and transplanting the exposed mixture into the patient.
地址 Saint Lambert, QC CA