BIOSYNCHRONOUS TRANSDERMAL DRUG DELIVERY

摘要

Systems and methods for synchronizing the administration of compounds with the human body's natural circadian rhythms and addiction rhythms to counteract symptoms when they are likely to be at their worst by using an automated and preprogrammable transdermal or other drug administration system.

主权项

1. A method of delivering nicotine to a subject, the method comprising:
wearing an automated transdermal drug delivery device during the subject's sleep such that a permeable membrane of the automated transdermal drug delivery device is in contact with skin of the subject; and beginning to deliver a substance comprising nicotine from a reservoir of the transdermal drug delivery device to the permeable membrane during a one hour period immediately prior to the subject's waking to transdermally administer nicotine to the subject.