| 发明名称 |
Succinate Prodrugs for Use in the Treatment of Lactic Acidosis or Drug-Induced Side-Effects Due to Complex I-Related Impairment of Mitochondrial Oxidative Phosphorylation |
| 摘要 |
The present invention relates to a succinate prodrug for use in the treatment or prevention of lactic acidosis. |
| 申请公布号 |
US2017100359(A1) |
申请公布日期 |
2017.04.13 |
| 申请号 |
US201615128496 |
申请日期 |
2016.04.08 |
| 申请人 |
NEUROVIVE PHARMACEUTICAL AB |
发明人 |
Elmer Eskil;Hansson Magnus Joakim;Ehinger Karl Henrik Johannes;Piel Sarah;Moss Steven |
| 分类号 |
A61K31/225;A61K31/155;A61K45/06 |
主分类号 |
A61K31/225 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for treating or preventing i) lactic acidosis, ii) side-effect related to a Complex I defect, inhibition or malfunction, or iii) side-effects related to defect, inhibition or malfunction in aerobic metabolism upstream of complex I in a subject, said method comprising administering an effective amount of a succinate prodrug to the subject. |
| 地址 |
Lund SE |
