发明名称 RAS INHIBITORY PEPTIDES AND USES THEREOF
摘要 The present invention provides peptides comprising a sequence of X-6X-5X-4X-3X-2X-1X1PX3X4PX6X7PGX10X11AX13X14X15X16LX18X19X20X21X22X23LX25X26YLX29X30X31X32 wherein the amino acids X-6, X-5, X-4, X-3, X-2, X-1, X1 X3, X4, Χ6, Χ7, Χ10, X11, X13, X14, X15, X16, X18, X19, X20, X21, X22, X25, X26, X29, X30, X31, and X32 are as defined herein. The present invention further provides pharmaceutical compositions comprising the peptides and methods of using the peptides. Also provided are methods of screening a library of peptide dimers using a peptide dimer display technology.
申请公布号 EP3145523(A2) 申请公布日期 2017.03.29
申请号 EP20150796407 申请日期 2015.05.21
申请人 President and Fellows of Harvard College 发明人 VERDINE, Gregory, L.;MCGEE, John, Hanney
分类号 A61K38/00 主分类号 A61K38/00
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