| 摘要 |
The present invention encompasses combinations comprising a plurality of amino acids, formulations thereof for use in humans and animals, as well as methods for increasing muscle protein synthesis, muscle strength, and/or muscle function in a subject with chronic heart failure, cardiac cachexia or a combination thereof. |
| 主权项 |
1. A method for increasing muscle protein synthesis, increasing muscle strength, increasing muscle function, or a combination thereof, the method comprising administering to a subject with chronic heart failure, cardiac cachexia or a combination thereof a combination comprising phenylalanine, valine, threonine, tryptophan, methionine, leucine, isoleucine, lysine, histidine, citrulline and L-carnitine in a w/w ratio of about 4:about 6:about 5:about 2:about 2:about 25:about 7:about 10:about 1:about 8:about 3, respectively, and biotin, omega-3 fatty acids, or a combination thereof. |
