发明名称 |
TrkA KINASE INHIBITORS, COMPOSITIONS AND METHODS THEREOF |
摘要 |
The present invention is directed to benzyl urea compounds of formula (I) which are tropomyosin-related kinase (Trk) family protein kinase inhibitors, and hence may be useful in the treatment of pain, inflammation, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination or a disease or disorder associated with abnormal activities of nerve growth factor (NGF) receptor Trk-A, Trk-B and/or Trk-C. |
申请公布号 |
EP3046554(A4) |
申请公布日期 |
2017.03.08 |
申请号 |
EP20140845934 |
申请日期 |
2014.09.17 |
申请人 |
Merck Sharp & Dohme Corp. |
发明人 |
COOKE, Andrew, J.;STUMP, Craig, A.;ZHANG, Xu-Fang;LI, Chun Sing;MAO, Qinghua |
分类号 |
A61K31/17;A61K31/41;A61P29/00 |
主分类号 |
A61K31/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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