| 发明名称 |
SMALL MOLECULE INHIBITORS OF KU70/80 AND USES THEREOF |
| 摘要 |
Provided herein are methods for identifying and treating subjects having conditions involving aberrant Ku70/80 activity. In particular, the invention relates to small-molecules which function as inhibitors of Ku70/80 protein and the non-homologous end-joining (NHEJ) pathway, and their use as therapeutics for the treatment of cancer and other diseases. |
| 申请公布号 |
WO2017031116(A1) |
申请公布日期 |
2017.02.23 |
| 申请号 |
WO2016US47173 |
申请日期 |
2016.08.16 |
| 申请人 |
THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA |
发明人 |
WETERINGS, Eric;MAHADEVAN, Daruka;VAGNER, Josef |
| 分类号 |
A61K31/496;A61K31/55;C07D413/12 |
主分类号 |
A61K31/496 |
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