| 摘要 |
Disclosed herein are antisense compounds and methods for decreasing SOD-1 mRNA and protein expression. Such methods, compounds, and compositions are useful to treat, prevent, or ameliorate SOD-1 associated diseases, disorders, and conditions. Such SOD-1 associated diseases include amyotrophic sclerosis (ALS). |
| 申请人 |
Ionis Pharmaceuticals, Inc. |
发明人 |
SWAYZE, Eric, E.;COLE, Tracy;KORDASIEWICZ, Holly;FREIER, Susan, M.;CONDON, Thomas, P.;WANCEWICZ, Edward;LOCKHART, Trisha;VICKERS, Timothy;SINGH, Priyam |
