| 摘要 |
Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs/therapeutic agents within the GI tract. Many embodiments provide swallowable devices for delivering the agents. Particular embodiments provide a swallowable device for delivering drugs into the intestinal wall (IW). Embodiments also provide preparations including a plurality of glucose regulating compounds (GRC) that are configured to be contained within the capsule, advanced from the capsule into the IW and degrade to release the drug into the bloodstream to produce a therapeutic effect. The preparation can be operably coupled to delivery means having a first configuration where the preparation is contained in the capsule and a second configuration where the preparation is advanced out of the capsule into the IW. Particular embodiments provide therapeutic preparations comprising insulin, GLP-1 and a third GRC where the third compound interacts with insulin or GLP-1 to produce an enhanced therapeutic effect in the patient. |
