发明名称 CANCER TREATMENTS USING COMBINATIONS OF TYPE 2 MEK AND ERK INHIBITORS
摘要 The present invention provides, inter alia, methods, kits, and pharmaceutical compositions for treating or ameliorating the effects of a cancer in a subject in need thereof. The method includes administering to the subject an effective amount of (i) a first anti-cancer agent, which is BVD 523 or a pharmaceutically acceptable salt thereof and (ii) a second anti-cancer agent, which is a type 2 MEK inhibitor, or other MEK inhibitors, or pharmaceutically acceptable salts thereof, to treat or ameliorate the effects of the cancer. Additional methods for effecting cancer cell death are also provided.
申请公布号 EP3082779(A1) 申请公布日期 2016.10.26
申请号 EP20140871217 申请日期 2014.12.19
申请人 BIOMED VALLEY DISCOVERIES, INC. 发明人 SAHA, SAURABH;WELSCH, DEAN;DECRESCENZO, GARY;ROIX, JEFFREY JAMES
分类号 A61K31/00 主分类号 A61K31/00
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