发明名称 |
CARBOXYLIC ACID ESTER PRODRUG INHIBITORS OF MEK |
摘要 |
The invention generally relates to compounds having structure I: wherein x represents alkyl, aryl or het-aryl, each of y independently represents hydrogen or halogen and z represents hydrogen or alkyl. Further, said compounds are inhibitors of MEK 1, 2 and 5. Furthermore, the invention includes methods of making said compounds, compositions including said compounds and uses for inhibiting MEK 1, 2 and 5. |
申请公布号 |
EP2920144(A4) |
申请公布日期 |
2016.06.29 |
申请号 |
EP20130855132 |
申请日期 |
2013.11.15 |
申请人 |
DUQUESNE UNIVERSITY OF THE HOLY SPIRIT |
发明人 |
CHAKRABARTY, SURAVI;MONLISH, DARLENE;FLAHERTY, PATRICK;CAVANAUGH, JANE E.;POTDAR, SNEHA |
分类号 |
C07C229/58 |
主分类号 |
C07C229/58 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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