ARTICLE COMPRISING A MICRONEEDLE

摘要

An article 100 comprising at least one microneedle 160 is provided. The article comprises a first side 112 and a second side 114 opposite the first side. The first side comprises a central cavity portion 120 and a platform portion 130, with at least one microneedle extending therefrom, wherein the platform portion is not coplanar with the central cavity portion. The platform portion substantially surrounds the central cavity portion. The at least one microneedle 160 comprises a body comprising an outer surface 163; a base segment 166 having a base and a first shape; a tip segment 168 having a tip 164 and a second shape, wherein the second shape is distinct from the first shape; a transition plane 167 that delineates the base segment and the tip segment; and a central axis.

主权项

1. An article, comprising:
a first side comprising a central cavity portion and a platform portion that projects from the first side and that is not coplanar with the central cavity portion; a second side opposite the first side; and at least three hollow microneedles extending from the platform portion in a first direction; wherein the platform portion substantially surrounds the central cavity portion; wherein the platform portion comprises an inner perimeter proximate the central cavity portion and an outer perimeter distal the central cavity portion; wherein the at least three hollow microneedles each comprise a body that comprises:
an outer surface;a base segment having a base and a first shape that is defined by a first section of the outer surface;a tip segment having a tip and a second shape that is defined by a second section of the outer surface, wherein the second shape is distinct from the first shape;a transition plane that delineates the base segment and the tip segment; anda central axis; wherein a first angle, defined by the central axis of each of the at least three hollow microneedles and a shortest line extending from the outer perimeter of the platform and through the transition plane of the microneedle, is less than about 50°.