Controlled release compositions and methods of using

摘要

Cyclodextrin compositions, including a hydrophobic carrier and a cyclodextrin complex, are formed and disposed on a variety of substrates using conditions that avoid substantial loss of the complexed compound from the cyclodextrin complex, even where the complexed compound is a gas a common ambient temperatures (e.g. 20° C.). Flexographic printing is particularly useful for disposing the cyclodextrin compositions on one or more substrates. Substrates treated with the cyclodextrin complexes are useful for subsequent release of the complexed compound.

主权项

1. A method of making a treated substrate, the method comprising
heating the composition to a temperature between 60° C. and 80° C., the composition consisting essentially of
a cyclodextrin inclusion complex comprising a cyclodextrin compound and an olefinic inhibitor; anda carrier comprising petrolatum or a petrolatum-like material, wherein the carrier has a melting transition onset between about 23°C and 40°C, and solubility in water of less than 1 wt % at 25°C; and disposing the heated composition on a first substrate using a flexographic printing press.