发明名称 Levodopa prodrug compounds, compositions comprising the same and uses thereof
摘要 Provided is a levodopa prodrug that overcomes the problems attributed to the blood kinetics of levodopa such as large number of doses and the incidence of side effects due to frequent dosing. (2S)-2-Amino-3-(3,4-bis((2-(benzoyloxy)-2-methylpropanoyl)oxy)phenyl)propanoic acid, a salt thereof, or a solvate thereof is a levodopa prodrug, and provides a flat blood concentration-time profile of levodopa through oral administration, and therefore is useful as a preventive and/or therapeutic agent for Parkinson's disease and/or Parkinson's syndrome that overcomes the problems associated with pharmaceutical preparations of levodopa.
申请公布号 IL226672(A) 申请公布日期 2016.04.21
申请号 IL20130226672 申请日期 2013.05.30
申请人 ONO PHARMACEUTICAL CO. LTD. 发明人
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