发明名称 |
uso de um composto da fórmula (i),(ii),(iii), ou (iv) ou um sal farmaceuticamente aceitável seu para a fabricação de um medicamento para o tratamento de câncer em um humano ou um animal; método para o tratamento de câncer, pacote comercial, método para redução de células cancerosas e kit para o tratamento de câncer |
摘要 |
This invention provides a medicament for the treatment of cancer, which cause a reduction of cancer. This invention relates to use of a compound which has inhibitory activities against prostaglandin E2 receptor (EP4 receptor) and is represented by the following general formula (I), (II), (III), or (IV), or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising the compound or the salt for the manufacture of a medicament for the treatment of cancer. The invention relates to a method for treatment of cancer comprising administering the compound or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising the compound or the salt to humans or animals. The compound or a pharmaceutically acceptable salt thereof, or the pharmaceutical composition may be used in combination with one or more second active agents. |
申请公布号 |
BRPI1014174(A2) |
申请公布日期 |
2016.04.05 |
申请号 |
BR2010PI14174 |
申请日期 |
2010.04.22 |
申请人 |
RAQUALIA PHARMA INC. |
发明人 |
KAZUHIKO NONOMURA;SHINICHI KOIZUMI;TAKAKO OKUMURA;YUKINORI TAKE |
分类号 |
C07D213/64;A61K31/192;A61K31/437;A61K31/4412;A61P35/00;A61P43/00;C07D471/04 |
主分类号 |
C07D213/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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