发明名称 DIAGNOSIS AND TREATMENT RELATING TO TH2 INHIBITION
摘要 PROBLEM TO BE SOLVED: To provide methods for diagnosing and treating diseases related to TH2 inhibition including but not limited to asthma.SOLUTION: Provided is a method for identifying patients of asthma or respiratory diseases having a potential to response to the treatment with a TH2 pathway inhibitor, which method comprises determining whether the patient is eosinophilic inflammation positive (EIP) or not by using eosinophilic inflammation diagnostic assay (EIDA), where EIP status shows the possibility of the patient to respond the treatment with a TH2 pathway inhibitor. The patient to be treated with a TH2 pathway inhibitor is a moderate to severe asthma patient not controllable with a corticosteroid prior to the treatment, and then treated with the TH2 pathway inhibitor (anti-IL-13 antibody) and one, two, three or more controllers.SELECTED DRAWING: None
申请公布号 JP2016041689(A) 申请公布日期 2016.03.31
申请号 JP20150160118 申请日期 2015.08.14
申请人 GENENTECH INC 发明人 JOSEPH R ARRON;RICHARD W ERICKSON;MICHELLE FREEMER;MEREDITH HAZEN;JIA GUIQUAN;JOHN G MATTHEWS;WENDY PUTNAM;HELEEN SCHEERENS;ZHENG YANAN
分类号 A61K39/395;A61K31/573;A61K45/00;A61P11/06;G01N33/53 主分类号 A61K39/395
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