| 发明名称 |
Fluorinated Derivatives of 3-Hydroxypyridin-4-Ones |
| 摘要 |
Compounds of Formula I which are derivatives of 3-Hydroxypyridin-4-ones. The compounds may be used in treatment of a medical condition related to a toxic concentration of iron. The compounds may be used for preparation of a medicament for treatment of a medical condition related to a toxic concentration of iron. The medical condition related to a toxic concentration of iron may be selected from the group consisting of: cancer, pulmonary disease, progressive kidney disease and Friedreich's ataxia. |
| 申请公布号 |
US2016083346(A1) |
申请公布日期 |
2016.03.24 |
| 申请号 |
US201514956029 |
申请日期 |
2015.12.01 |
| 申请人 |
Apotex Technologies Inc. |
发明人 |
Tam Tim Fat;Leung-Toung Regis;Wang Yingsheng;Zhao Yanqing;Xin Tao;Shah Birenkumar;N'Zemba Blaise;Wodzinska Jolanta Maria;Premyslova Maryna |
| 分类号 |
C07D213/69 |
主分类号 |
C07D213/69 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A compound of Formula I: wherein G1 is H, C1-C4 alkyl or CH2OH; G2 is (CH2)nCF2R3, where n is 1, and R3 is H or F; G3 is H or C1-C4 alkyl; and G4 is H. |
| 地址 |
Toronto CA |
