发明名称 Multicomponent crystalline system comprising deferasirox and isonicotinamide and a process for the preparation thereof
摘要 The present invention refers to a multicomponent crystalline system (co-crystal) comprising a compound of formula (1) (4-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic acid; INN: Deferasirox) formula (1) and a compound of formula (2) (Isonicotinamide; pyridine-4-carboxamide) formula (2), as well as to a process for obtaining the same.;
申请公布号 US9290452(B2) 申请公布日期 2016.03.22
申请号 US201314415875 申请日期 2013.08.05
申请人 BASF SE 发明人 Hafner Andreas;Blatter Fritz;Roedel Eva;Szelagiewicz Martin;Chiodo Tiziana;Hintermann Tobias;Salvador Beate;Vossen Marcus
分类号 C07D213/81;C07D249/08 主分类号 C07D213/81
代理机构 Oblon, McClelland, Maier & Neustadt, L.L.P 代理人 Oblon, McClelland, Maier & Neustadt, L.L.P
主权项 1. A multicomponent crystalline system, comprising a compound of formula 1, which is 4-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic acid: and a compound of formula 2, which is isonicotinamide; pyridine-4-carboxamide:
地址 Ludwigshafen DE