发明名称 ANTI-VEGF/DLL4 DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF.
摘要 Disclosed herein are multivalent and multispecific binding proteins, methods of making the binding proteins, and their uses in the diagnosis, monitoring, inhibition, prevention and/or treatment of cancers, tumors, and/or other angiogenesis-dependent diseases diseases characterized by aberrant DLL4 and/or VEGF expression or activity.
申请公布号 MX2015005593(A) 申请公布日期 2016.02.05
申请号 MX20150005593 申请日期 2013.10.31
申请人 ABBVIE INC. 发明人 JIJIE GU;JONATHAN A. HICKSON;RAVI CHARI;DEANNA L. HAASCH;SUPRIYA GUPTA;CAMELLIA ZAMIRI;DOMINIC J. AMBROSI;SUSAN E. LAPPE;YINGCHUN LI;LOUIE NAUMOVSKI;XIANHUA CAO
分类号 C07K16/18;A61K39/00;C07K16/22;C07K16/46 主分类号 C07K16/18
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