发明名称 |
SUBSTITUTED BICYCLIC DIHYDROPYRIMIDINONES AND THEIR USE AS INHIBITORS OF NEUTROPHIL ELASTASE ACTIVITY |
摘要 |
This invention relates to substituted bicyclic dihydropyrimidinones of formula 1 and their use as inhibitors of neutrophil elastase activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of pulmonary, gastrointestinal and genitourinary diseases, inflammatory diseases of the skin and the eye and other autoimmune and allergic disorders, allograft rejection, and oncological diseases. |
申请公布号 |
WO2016016364(A1) |
申请公布日期 |
2016.02.04 |
申请号 |
WO2015EP67499 |
申请日期 |
2015.07.30 |
申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH |
发明人 |
GNAMM, CHRISTIAN;ANDERSKEWITZ, RALF;HOESCH, HOLGER;MORSCHHAEUSER, GERD;OOST, THORSTEN;PETERS, STEFAN;RIES, UWE JOERG |
分类号 |
C07D471/04 |
主分类号 |
C07D471/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|