发明名称 |
TREATMENT OF INSULIN RESISTANCE ASSOCIATED WITH PROLONGED PHYSICAL INACTIVITY |
摘要 |
Insulin resistance biomarkers and related methods of using the biomarkers are provided. The biomarkers may be blood biomarkers and include C-peptide, Insulin-Like Growth Factor-Binding Protein 2 (IGFBP-2), and Leptin. Also provided is a method of reducing the effect of prolonged physical inactivity on insulin resistance in a subject who is experiencing prolonged physical inactivity, or who is expected to experience prolonged physical inactivity in the near future. |
申请公布号 |
US2016022617(A1) |
申请公布日期 |
2016.01.28 |
申请号 |
US201414775972 |
申请日期 |
2014.03.14 |
申请人 |
ABBOTT LABORATORIES |
发明人 |
Luo Menghua;Pereira Suzette;Edens Neile;Davis Gerard;Gawel Susan;Chandran Raj |
分类号 |
A61K31/19;G01N33/68 |
主分类号 |
A61K31/19 |
代理机构 |
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代理人 |
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主权项 |
1. A method of reducing the effect of prolonged physical inactivity on insulin resistance in a subject who is experiencing or is expected to experience prolonged physical inactivity in the near future, the method comprising: administering a therapeutically effective amount of β-hydroxy-β-methylbutyric acid (HMB) or a salt thereof to the subject. |
地址 |
Abbott Park IL US |