发明名称 TREATMENT OF INSULIN RESISTANCE ASSOCIATED WITH PROLONGED PHYSICAL INACTIVITY
摘要 Insulin resistance biomarkers and related methods of using the biomarkers are provided. The biomarkers may be blood biomarkers and include C-peptide, Insulin-Like Growth Factor-Binding Protein 2 (IGFBP-2), and Leptin. Also provided is a method of reducing the effect of prolonged physical inactivity on insulin resistance in a subject who is experiencing prolonged physical inactivity, or who is expected to experience prolonged physical inactivity in the near future.
申请公布号 US2016022617(A1) 申请公布日期 2016.01.28
申请号 US201414775972 申请日期 2014.03.14
申请人 ABBOTT LABORATORIES 发明人 Luo Menghua;Pereira Suzette;Edens Neile;Davis Gerard;Gawel Susan;Chandran Raj
分类号 A61K31/19;G01N33/68 主分类号 A61K31/19
代理机构 代理人
主权项 1. A method of reducing the effect of prolonged physical inactivity on insulin resistance in a subject who is experiencing or is expected to experience prolonged physical inactivity in the near future, the method comprising: administering a therapeutically effective amount of β-hydroxy-β-methylbutyric acid (HMB) or a salt thereof to the subject.
地址 Abbott Park IL US