| 发明名称 |
COMPOSITION AND METHOD FOR PREVENTION, MITIGATION OR TREATMENT OF AN ENTEROPATHOGENIC BACTERIAL INFECTION |
| 摘要 |
Bicyclic compounds for decreasing the expression of bacterial virulence factors thereby preventing, mitigating, or treating bacterial infection are provided. |
| 申请公布号 |
US2015361045(A1) |
申请公布日期 |
2015.12.17 |
| 申请号 |
US201514837139 |
申请日期 |
2015.08.27 |
| 申请人 |
Trustees of Dartmouth College |
发明人 |
Kull F. Jon;Taylor Ronald K.;Gribble Gordon W.;Onyango Evans O.;Kelley Anne R. |
| 分类号 |
C07D217/12;A23L1/30;C07D209/12;C07D215/14;C07C59/84;C07C57/40 |
主分类号 |
C07D217/12 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A compound having the structure of Formula I, or a hydrate, isomer, prodrug or pharmaceutically acceptable salt thereof:wherein R1 is hydrogen or a polar group; R2 is hydrogen, alkenyl, or oxo; X is —CHCH—, —NH—, —C═N—, —N═C—, —C—NH— or —NH—C—; n is 0-6; and dashed lines represent bonds that are independently present or absent. |
| 地址 |
Hanover NH US |
