发明名称 |
UGT1A6 GENE SNP MARKERS ASSOCIATED WITH SERUM BILIRUBIN CONCENTRATION AND USES THEREOF |
摘要 |
<p>PURPOSE: A kit for predicting blood bilirubin concentration of a test sample and a method for detecting a bilirubin marker are provided to easily diagnose hyperbilirubinemia. CONSTITUTION: A kit for predicting blood bilirubin concentration of a test sample contains: 8-100 sequential nucleotide sequences having single nucleotide polymorphism(SNP) positioned at 301th nucleotide of sequence number 1-4, 8-11 and 13, 314th nucleotide of sequence number 5, 201th nucleotide of sequence number 6, 234th nucleotide of sequence number 7, 308th nucleotide of sequence number 12, 307th nucleotide of sequence number 14, and 136th nucleotide of sequence number 15; and a complementary nucleotide thereof. The prediction of bilirubin concentration is used for diagnosing hyperbilirubinemia, jaundice, Gilbert syndrome, Dubin-Johnson syndrome, Rotor syndrome, or Crigler-najjar syndrome.</p> |
申请公布号 |
KR20110002748(A) |
申请公布日期 |
2011.01.10 |
申请号 |
KR20090060384 |
申请日期 |
2009.07.02 |
申请人 |
KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY;KOREA INSTITUTE OF ORIENTAL MEDICINE |
发明人 |
KIM, YONG SUNG;KIM, SEON YOUNG;KANG, TAE WOOK;JEON, YEO JIN;KIM, HEE JIN;KIM, JEONG HWAN;PARK, JONG LYUL;KIM, JONG YEOL;LEE, SI WOO;JANG, EUN SU;JEONG, SANG KYUN |
分类号 |
C12Q1/68;C12N15/11 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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