发明名称 IMPROVED AMINO ACID SEQUENCES DIRECTED AGAINST HUMAN RESPIRATORY SYNCYTIAL VIRUS (HRSV) AND POLYPEPTIDES COMPRISING THE SAME FOR THE PREVENTION AND/OR TREATMENT OF RESPIRATORY TRACT INFECTIONS
摘要 <p>Amino acid sequences are provided that are directed against and/or that can specifically bind protein F of hRSV, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences. The amino acid sequences, polypeptides and therapeutic compounds and compositions provided by the invention show an improved stability, less immunogenicity and/or improved affinity and/or avidity for protein F of hRSV. The invention also relates to the uses of such amino acid sequences, polypeptides, compounds or constructs for prophylactic and/or therapeutic purposes.</p>
申请公布号 CA2764398(A1) 申请公布日期 2010.12.09
申请号 CA20102764398 申请日期 2010.06.07
申请人 ABLYNX NV 发明人 DEPLA, ERIK;STORTELERS, CATELIJNE;STAELENS, STEPHANIE
分类号 C07K16/10 主分类号 C07K16/10
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