| 摘要 |
PROBLEM TO BE SOLVED: To produce a cosmetic achieving unprecedentedly high safety and effect and having a skin barrier improving function.SOLUTION: Using a cosmetic prepared by blending a component (A) as a clock gene BMAL-1 protein production promotion active substance, a component (B), and a component (C); action on skin cells to make the cells themselves promote production of moisturizing ingredients and strong action to enhance a skin barrier function are achieved, and an effect to ameliorate atopic symptoms such as itching and dry skin can be expected. The cosmetic is highly safe and can be used without any worry. The component (A) is one or more selected from nicotinamide, calcium pantothenate, and a Salvia officinalis extract. The component (B) is a menthol ester of a fatty acid. The component (C) is one or more selected from diisopropyl sebacate, menthoxy propanediol, and bis ethoxydiglycol cyclohexane-1,4-dicarboxylate. |
