主权项 |
1. A method for producing a tissue-engineered material in a peritoneal cavity of a living subject, said method comprising the following steps of:
(a) implanting a hollow member in the peritoneal cavity, wherein the hollow member is made of a biocompatible and fluid-impermeable material that is expansible and contractible and is positioned in the peritoneal cavity in a manner that a part of the hollow member contacts an inner wall surface of the peritoneal cavity for enabling formation of a biological tissue that encapsulates the hollow member; and (b) during a stimulation session, providing a periodic mechanical stimulus to the biological tissue being formed on the hollow member by periodically introducing a fluid to flow into and out of the hollow member to cause the hollow member to expand and contract accordingly; wherein, in step (a), the hollow member has an elastic segment that has opposite ends, that is elastically deformable, and that is disposed in the peritoneal cavity, and a pair of securing subcutaneous segments that extend from and are in fluid communication with the opposite ends of the elastic segment respectively, that extend outwardly of the peritoneal cavity, and that position the elastic segment in the peritoneal cavity. |