摘要 |
FIELD: chemistry.SUBSTANCE: invention relates to method of obtaining substituted 3-formylindole-5,6-dicarbonitrileswhere R = ALK, or Ar, or Het, which can be applied as precursors for synthesis of biologically active substances, medicinal substances. Method of obtaining 3-formylindole-5,6-dicarbonitriles consists in interaction of 2-substituted 1-methoxyindole-5,6-dicarbonitriles with phosphoryl-chloride.EFFECT: application of claimed method of synthesis of substituted 3-formylindole-5,6-dicarbonitriles makes it possible to obtain novel ortho-dicarbonitriles, which contain indole cycle, which have not been described in literature before.4 ex |