SYSTEMS, DEVICES, AND METHODS FOR MODULATING RENAL NERVE TISSUE

摘要

Methods for treating a patient using therapeutic renal neuromodulation and associated devices, system, and methods are disclosed herein. One aspect of the present technology is directed to neuromodulating nerve tissue in selected anatomical regions. In one embodiment, the method can include intravascularly advancing an elongate shaft of a catheter to renal vasculature of a human patient and locating a first neuromodulation element of the catheter within a distalmost portion of a main renal artery. The method includes locating a second neuromodulation element of the catheter within a branch vessel of the renal artery distal to a bifurcation at a distal end of the main renal artery. Neuromodulation of the nerve tissue surrounding the selected anatomical treatment locations can inhibit sympathetic neural activity in nerves proximate a portion of a renal artery and/or a renal branch artery proximate a renal parenchyma.

主权项

1. A method, comprising:
intravascularly advancing an elongate shaft of a catheter to renal vasculature of a human patient; locating a first neuromodulation element of the catheter within a distalmost portion of a main renal artery directly connected to an aorta of the patient and extending distally toward a kidney of the patient; locating a second neuromodulation element of the catheter within a branch vessel of the renal artery distal to a bifurcation at a distal end of the main renal artery; modulating nerve tissue within an anatomical region extending about the distalmost portion of the main renal artery via the first neuromodulation element; and modulating nerve tissue within an anatomical region extending about the branch vessel via the second neuromodulation element.