Method and Apparatus for Multi-spectral Imaging and Analysis of Skin Lesions and Biological Tissues

摘要

A multispectral nevoscope that uses specific wavelengths in the visible and infrared spectrum of electromagnetic radiation to transilluminate a skin-lesion or a biological tissue or specimen for imaging and maps multispectral 2-dimensional images into 3-dimensional virtual space for providing 3-D distributions of pre-defined parameters representing the characteristic properties (such as melanin, hemoglobin and deoxyhemoglobin, etc.) of a skin lesion. Methods are disclosed for analyzing and using the characteristic distributions of specific parameters for detection and management of skin-cancers, or characterization of a biological tissue or specimen.

主权项

1. A multispectral nevoscope for examining in situ a skin lesion of a patient, comprising:
(a) a housing having a central axis and a base with a central aperture for positioning over a portion of skin of a patient, the portion of skin including the lesion to be examined; (b) a face plate positioned in register with the central aperture comprising an imaging area having plural illumination fiber channels operably connected to an illuminator-filter assembly and plural receiver fiber channels; and (c) at least one transillumination device disposed proximal to the faceplate operable to transmit light in a converging ring into the skin of the patient in the region of the lesion to uniformly transilluminate the region of skin of the patient including the lesion.