发明名称 |
Tadalafil free base-containing film dosage form containing polyethylene glycol-based polymer and/or vinyl pyrrolidone-based polymer as dispersion stabilizer |
摘要 |
The present invention relates to a film preparation for oral administration, containing tadalafil free base, and a preparation method therefor. By adding a polyethylene glycol-based polymer and/or a vinyl pyrrolidone-based polymer as a dispersion stabilizer, it is possible to: maximize the dispersion stability of tadalafil free base in a film by using a small amount without inducing a specific odor or taste which can occur when using other dispersion stabilizers known in the relevant art; provide a film having an extremely low rate of tadalafil free base particle reaggregation; and remarkably reduce the amount of bubbles during a preparation process. |
申请公布号 |
AU2014251532(A1) |
申请公布日期 |
2015.11.12 |
申请号 |
AU20140251532 |
申请日期 |
2014.04.11 |
申请人 |
CTC BIO, INC. |
发明人 |
JEON, HONG RYEOL;KWON, DO-WOO;LEE, BONG-SANG;PARK, SU-JUN;CHA, BONG-GEUN;KIM, JUN-KI;HAN, JIYEONG;KIL, MYEONGCHEOL |
分类号 |
A61K9/70;A61K47/30;A61K47/38 |
主分类号 |
A61K9/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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