发明名称 |
DEVICES AND METHODS FOR THE RAPID AND ACCURATE DETECTION OF ANALYTES |
摘要 |
<p>Disclosed are field effect transistor-based (FET-based) sensors for the rapid and accurate detection of analytes both in vivo and in vitro. The FET-based sensors can include a substrate, a channel disposed on the substrate, a source electrode and a drain electrode electrically connected to the channel, and a recognition element for an analyte of interest immobilized on the surface of the channel via a linking group. The distance between the recognition element and the channel can be configured such that association of the analyte of interest with the recognition element induces a change in the electrical properties of the channel. In this way, an analyte of interest can be detected by measuring a change in an electrical property of the channel. Also provided are devices, including probes and multi-well plates, incorporating the FET-based sensors.</p> |
申请公布号 |
EP2807479(A4) |
申请公布日期 |
2015.11.04 |
申请号 |
EP20130741590 |
申请日期 |
2013.01.23 |
申请人 |
THE OHIO STATE UNIVERSITY |
发明人 |
LEE, STEPHEN C.;LU, WU;BRILLSON, LEONARD JACK;HADLEY, GREGG A.;ADAMS, PATRICK;PELLETIER, RONALD P.;BERGER, PAUL RAYMOND |
分类号 |
G01N27/414;A61B5/00;A61B5/145;A61B5/1473;A61B5/1486 |
主分类号 |
G01N27/414 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|