发明名称 |
Hydrogel-Driven Drug Dosage Form |
摘要 |
A controlled release dosage form has a coated core with the core comprising a drug-containing composition and a water-swellable composition, each occupying separate regions within the core. The drug-containing composition comprises a low-solubility drug and a drug-entraining agent. The coating around the core is water-permeable, water-insoluble and has at least one delivery port therethrough. A variety of formulations having specific drug release profiles are disclosed.
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申请公布号 |
US2007087057(A1) |
申请公布日期 |
2007.04.19 |
申请号 |
US20060610603 |
申请日期 |
2006.12.14 |
申请人 |
PFIZER INC |
发明人 |
APPEL LEAH E.;BEYERINCK RONALD A.;CHIDLAW MARK B.;CURATOLO WILLIAM J.;FRIESEN DWAYNE T.;SMITH KELLY L.;THOMBRE AVINASH G. |
分类号 |
A61K9/22;A61K9/24;A61K9/00;A61K9/28;A61K9/36;A61K47/36;A61K47/38 |
主分类号 |
A61K9/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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