HYDROXYLATED PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS
摘要
The present invention provides compounds, including pharmaceutically acceptable salts thereof, comprising the Formula (I): Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases, such as cancer.
申请公布号
EP2247578(A1)
申请公布日期
2010.11.10
申请号
EP20090700422
申请日期
2009.01.09
申请人
ARRAY BIOPHARMA, INC.;GENENTECH, INC.
发明人
BENCSIK, JOSEF R.;BLAKE, JAMES F.;KALLAN, NICHOLAS C.;MITCHELL, IAN S.;SPENCER, KEITH LEE;XIAO, DENGMING;XU, RUI;CHABOT, CHRISTINE;DO, STEVEN;LIANG, JUN;SAFINA, BRIAN;ZHANG, BIRONG