| 发明名称 |
Substituted pyrazines as tubulin inhibitors |
| 摘要 |
Compounds of general formula (I), (II), (III) and (V) are described for use in modulating microtubule polymerization and in the treatment of associated disease states. Use of compounds (I), (III) and (V) in the treatment of kinase-associated disease states is also described. Further described are novel compounds of formula (II), (III) and (V).; |
| 申请公布号 |
US9139560(B2) |
申请公布日期 |
2015.09.22 |
| 申请号 |
US201414194543 |
申请日期 |
2014.02.28 |
| 申请人 |
YM Biosciences Australia Pty Ltd. |
发明人 |
Burns Christopher John;Wilks Andrew Frederick;Harte Michael Francis;Sikanyika Harrison;Fantino Emmanuelle |
| 分类号 |
A61K31/4965;C07D241/20;C07D401/12;C07D213/74;C07D239/42;C07D253/07;C07D401/14;C07D403/12 |
主分类号 |
A61K31/4965 |
| 代理机构 |
|
代理人 |
Dammann Yu-Ming |
| 主权项 |
1. A compound selected from the group consisting of: |
| 地址 |
Foster City CA US |
