REDUCTION OF TRAFL LEVELS COMBINED WITH NUTRIENT STRESS FOR TREATING LYMPHOCYTE-RELATED CANCERS
摘要
The present disclosure provides methods and uses for treating lymphocyte related cancers comprising administering a nutrient stress-inducing agent in combination with an agent that lowers the levels of or inhibits TRAF1. Also provided are methods of determining treatment for a subject with a lymphocyte related cancer and assays for identifying a PKN1 inhibitor.
申请公布号
CA2940660(A1)
申请公布日期
2015.09.11
申请号
CA20152940660
申请日期
2015.03.06
申请人
THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO;UNIVERSITY HEALTH NETWORK
发明人
ABDUL SATER, ALI;MCPHERSON, ANN JOSEPHINE;WATTS, TANIA HELEN;MINDEN, MARK;LAISTER, ROB