Prosthetic heart valve devices and associated systems and methods

摘要

Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include an expandable support having an outer surface and configured for placement between leaflets of the native valve. The device can also include a plurality of asymmetrically arranged arms coupled to the expandable support and configured to receive the leaflets of the native valve between the arms and the outer surface. In some embodiments, the arms can include tip portions for engaging a subannular surface of the native valve.

主权项

1. A prosthetic treatment apparatus for treating a native mitral valve having a native annulus and native leaflets, comprising:
a support having a downstream end configured to be positioned toward a left ventricle, an upstream end configured to be positioned toward a left atrium, and an interior, wherein the support is expandable from a low-profile configuration for implantation to an expanded configuration at a native mitral valve; a prosthetic valve having a tri-leaflet assembly mounted to the interior of the expandable support and adapted to allow blood flow in the downstream direction and to block blood flow in the upstream direction; a plurality of elongated members extending from a downstream portion of the support to which the prosthetic valve is attached and extending outwardly from the support in an upstream direction, wherein
the elongated members have sufficient flexibility to deflect inwardly or outwardly relative to the support to accommodate expansion or distortion of the native annulus,the elongated members are configured to inhibit movement of the support toward the left atrium,the prosthetic valve and the downstream portion of the support from which the elongated members extend remain fixed relative to each other along a longitudinal dimension of the support from the low-profile configuration to the expanded configuration,the elongated members are configured to remain inward of an inner surface of the native leaflets; andthe elongated members are biased outwardly in the expanded configuration to exert force against the inner surface of the native leaflets; and a skirt coupled to a downstream portion of the support and flaring outward in an upstream direction such that an upstream end of the flared portion is spaced outwardly from the support, wherein the skirt extends around the entire circumference of the support, and wherein the skirt is oriented on the device as to inhibit blood flow between the prosthetic treatment device and the native valve.