主权项 |
1. A method for determining a test patient's likelihood of cancer recurrence or cancer-specific death, comprising:
(1) measuring, in a sample obtained from said test patient, the expression levels of a panel of genes comprising at least 3 test genes selected from Panel F; (2) providing a test expression score by (a) weighting the determined expression of each gene in said panel of genes with a predefined coefficient (which may be 0), and (b) combining the weighted expression of each gene in said panel of genes to provide said test expression score, wherein said test genes are weighted to contribute at least 25% to said test expression score; and (3) diagnosing said test patient as having either (a) an increased likelihood of cancer recurrence or cancer-specific death based at least in part on said test expression score exceeding a first reference expression score or (b) no increased likelihood of cancer recurrence or cancer-specific death based at least in part on said test expression score not exceeding a second reference expression score. |