发明名称 |
NOVEL 3-(INDOL-3-YL)-PYRIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USE |
摘要 |
The present invention relates to compound of Formula (I) or pharmaceutically acceptable enantiomers, salts or solvates thereof. The invention further relates to the use of the compounds of Formula I as TDO2 inhibitors. The invention also relates to the use of the compounds of Formula I for the treatment and/or prevention of cancer, neurodegenerative disorders such as Parkinson's disease, Alzheimer's disease and Huntington's disease, chronic viral infections such as HCV and HIV, depression, and obesity. The invention also relates to a process for manufacturing compounds of Formula I. |
申请公布号 |
WO2015121812(A1) |
申请公布日期 |
2015.08.20 |
申请号 |
WO2015IB51036 |
申请日期 |
2015.02.11 |
申请人 |
ITEOS THERAPEUTICS |
发明人 |
CROSIGNANI, STEFANO;CAUWENBERGHS, SANDRA;DRIESSENS, GREGORY;DEROOSE, FREDERIK |
分类号 |
C07D401/14;A61K31/437;A61K31/4439;A61P3/04;A61P25/00;A61P31/12;A61P35/00;C07D401/04;C07D471/04 |
主分类号 |
C07D401/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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