MICRO-FLUIDIC PARTITIONING BETWEEN POLYMERIC SHEETS FOR CHEMICAL AMPLIFICATION AND PROCESSING

摘要

A system for fluid partitioning for chemical amplification or other chemical processing or separations of a sample, comprising a first dispenser of a first polymeric sheet, wherein the first polymeric sheet contains chambers; a second dispenser of a second polymeric sheet wherein the first dispenser and the second dispenser are positioned so that the first polymeric sheet and the second polymeric sheet become parallel; a dispenser of the fluid positioned to dispense the fluid between the first polymeric sheet and the second polymeric sheet; and a seal unit that seals the first polymeric sheet and the second polymeric sheet together thereby sealing the sample between the first polymeric sheet and the second polymeric sheet and partitioning the fluid for chemical amplification or other chemical processing or separations.

主权项

1. An apparatus for fluid partitioning for chemical amplification or other chemical processing or separations of a sample, comprising:
a first dispenser of a first polymeric sheet; a second dispenser of a second polymeric sheet wherein said first dispenser and said second dispenser are positioned so that said first polymeric sheet and said second polymeric sheet become parallel; a dispenser of the sample positioned to dispense the sample between said first polymeric sheet and said second polymeric sheet; and a seal unit that seals said first polymeric sheet and said second polymeric sheet together thereby sealing the sample between said first polymeric sheet and said second polymeric sheet and partitioning the sample for chemical amplification or other chemical processing or separations, wherein seal unit that seals said first polymeric sheet and said second polymeric sheet together comprises a roller with grid projections that forms a grid array in said first polymeric sheet and said second polymeric sheet.