| 发明名称 | Process for preparing a ketosulfone derivative | ||
| 摘要 | The present invention relates to a process for preparing a ketosulfone derivative and, more particularly, to an improved method for synthesizing 1-(6-methylpyridin-3-yl)-2-[(4-methylsulfonyl)-phenyl]ethanone by means of Pd-catalized alpha arylation process of a heteroaromatic ketone derivative. | ||
| 申请公布号 | US9085532(B2) | 申请公布日期 | 2015.07.21 |
| 申请号 | US201314382458 | 申请日期 | 2013.03.08 |
| 申请人 | ZACH SYSTEM S.P.A. | 发明人 | Melotto Elisa;Michieletto Ivan;Frega Vincenzo;Cotarca Livius;Verzini Massimo;Massaccesi Franco;Munari Ilaria |
| 分类号 | C07D211/70;C07D213/50 | 主分类号 | C07D211/70 |
| 代理机构 | Silvia Salvadori, P.C. | 代理人 | Silvia Salvadori, P.C. |
| 主权项 | 1. A process for the preparation of a compound of formula and salts thereof; which comprises reacting a compound of formula with a compound of formula wherein X is a halogen atom; in the presence of a catalyst, a ligand and a base; wherein said catalyst is a Pd catalyst complex and said ligand is an organophosphoric compound of formula 4,5-Bis-(diphenylphosphino)-9,9-dimethyl-xantene. | ||
| 地址 | Bresso IT | ||