摘要 |
A new platform method to purify plant-based monoclonal antibodies is provided. Such a method includes an antibody purification platform that involves a standardized procedure for the production of a wide array of different antibodies within a simplified context. The versatility of the overall purification process accords a one-size-fits-all approach for myriad antibody products and includes plant tissue harvesting, extraction and clarification, filtrate generation, a succession of column chromatography procedures, and buffer exposure to provide the desired monoclonal antibodies in proper filtered and purified form for further incorporation and/or use within medicaments and other formulations. Thus, the purified monoclonal antibodies produced thereby such a method are also encompassed within this invention. |
申请人 |
KENTUCKY BIOPROCESSING, INC. |
发明人 |
MORTON, JOSH;BRATCHER, BARRY;SWOPE, KELSI;HIATT, EMMETT, ERNEST, III;HUME, STEVEN, D.;ZEITLIN, LARRY |