发明名称 GUANIDINE COMPOUND
摘要 [Problem] The present invention provides a compound which is useful as an active ingredient of a pharmaceutical composition, in particular, a pharmaceutical composition for preventing and/or treating VAP-1-related diseases. [Means for Solution] The present inventors have conducted intensive studies on a compound having a VAP-1 inhibitory activity, and as a result, they have found that the compound or a salt thereof of the present invention exhibits an excellent VAP-1 inhibitory activity and is useful for preventing and/or treating VAP-1-related diseases, in particular, diabetic nephropathy or diabetic macular edema, thereby completing the present invention. In addition, the present invention relates to a pharmaceutical composition, in particular, a pharmaceutical composition for preventing and/or treating VAP-1-related diseases, which comprises the compound or a salt thereof of the present invention, and an excipient.
申请公布号 SG10201503044U(A) 申请公布日期 2015.06.29
申请号 SG10201503044U 申请日期 2012.03.13
申请人 ASTELLAS PHARMA INC. 发明人 YOSHIHARA, KOUSEI;SUZUKI, DAISUKE;YAMAKI, SUSUMU;YAMADA, HIROYOSHI;MIHARA, HISASHI;SEKI, NORIO
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