发明名称 OLIGONUCLEOTIDE INHIBITOR OF DNA POLYMERASES
摘要 The invention comprises a reversible oligonucleotide inhibitor of nucleic acid polymerases. Methods of designing said inhibitors and using said inhibitors in amplification and detection of nucleic acid, particularly detection of RNA by RT-PCR are also disclosed.
申请公布号 US2015176059(A1) 申请公布日期 2015.06.25
申请号 US201414562351 申请日期 2014.12.05
申请人 Roche Molecular Systems, Inc. 发明人 Fiss Ellen;San Filippo Joseph
分类号 C12Q1/68;C12N9/99;C12N15/113 主分类号 C12Q1/68
代理机构 代理人
主权项 1. A reversible inhibitor of nucleic acid polymerases comprising a single-stranded DNA oligonucleotide having one or more regions of double-stranded secondary structure, wherein at least one of said regions comprises at least one uracil base.
地址 Pleasanton CA US
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