发明名称 |
TRANSPOSON ACTIVATION DURING AGING AND NEURONAL DECLINE |
摘要 |
The present invention relates to transposon activation and mobilization, particularly in the brain, during normal aging; reporter systems to detect such mobilization, along with cells and transgenic animals containing such systems; methods of monitoring neuronal function during normal aging; methods of determining the risk of age-related neuronal decline and age-related mortality; and the use of transposon inhibitors and apoptosis inhibitors to delay age-related neuronal decline and age-related mortality. |
申请公布号 |
WO2014145613(A3) |
申请公布日期 |
2015.05.28 |
申请号 |
WO2014US30408 |
申请日期 |
2014.03.17 |
申请人 |
COLD SPRING HARBOR LABORATORY |
发明人 |
DUBNAU, JOSHUA;LI, WANHE;PRAZAK, LISA |
分类号 |
C12Q1/68;C12N15/113 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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