SITE-SPECIFIC INTEGRATION OF TRANSGENES INTO HUMAN CELLS
摘要
<p>Methods for inserting a polynucleotide sequence into the genome of a human cell are provided. The present methods result in insertion of a polynucleotide sequence of interest into the H11 locus in the genome of a human cell. Also provided are nucleic acids that include sequences for integrating a polynucleotide sequence of interest into the H11 locus in the genome of a human cell. A transgenic human cell including site specific recombination sites at the H11 locus is also disclosed.</p>
申请公布号
WO2015073703(A1)
申请公布日期
2015.05.21
申请号
WO2014US65513
申请日期
2014.11.13
申请人
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY