发明名称 |
Composite body for antigen or drug delivery |
摘要 |
The invention provides an antigen or drug delivery complex containing a complex of an antigen or drug and a cationic molecule, and an anionic molecule encapsulating the same. The antigen or drug delivery complex can be used as a main component of a drug delivery system that delivers various antigens and drugs to a particular cell or organ. |
申请公布号 |
US9028797(B2) |
申请公布日期 |
2015.05.12 |
申请号 |
US201113581194 |
申请日期 |
2011.02.24 |
申请人 |
Nagasaki University;Kyusyu University Corporation;National University Corporation Hamamatsu University School of Medicine |
发明人 |
Sasaki Hitoshi;Kurosaki Tomoaki;Kitahara Takashi;To Hideto;Yui Katsuyuki;Hirayama Kenji;Morita Kouichi;Mukai Takahiro;Magata Yasuhiro;Ogawa Mikako;Sano Kohei |
分类号 |
A61K49/00;A61K51/06;A61K31/711;A61K31/713;A61K39/00;A61K39/015;A61K39/145;A61K39/39;A61K47/48 |
主分类号 |
A61K49/00 |
代理机构 |
Leydig, Voit & Mayer, Ltd. |
代理人 |
Leydig, Voit & Mayer, Ltd. |
主权项 |
1. A method of imaging a lymph node in a mammal, comprising
(1) administering to the mammal a complex comprising
(a) a drug complex consisting of a nuclide for imaging, a cationic dendrimer and a chelating agent;(b) polyethylenimine; and(c) γ-polyglutamic acid, and (2) imaging the lymph node in the mammal. |
地址 |
Nagasaki JP |