发明名称 DIAGNOSING AND TREATING PATIENTS HAVING PSYCHIATRIC DISORDERS
摘要 Disclosed are methods and kits for diagnosing, prognosing, and treating patients having psychiatric disorders. The methods may include assessing whether a patient has a treatment resistant psychiatric disorder or assessing whether the patient is likely to develop a treatment resistant psychiatric disorder. The methods may include detecting genetic markers such as the single nucleotide polymorphism (SNP) in genes present in a genomic nucleic acid sample from the patient, and/or receiving, as a caregiver, the results of tests indicating whether the genetic markers are present in the genomic nucleic acid sample from the patient. The methods may include administering treatment to the patient, for example, based on the detected genetic markers, and administering treatment may include administering new antipsychotic drugs (APDs) that are trace amine-associated receptor 1 (TAAR1) agonists.
申请公布号 US2015099741(A1) 申请公布日期 2015.04.09
申请号 US201414506253 申请日期 2014.10.03
申请人 Northwestern University 发明人 Li Jiang;Meltzer Herbert Y.
分类号 A61K31/5513;A61K31/4045;C12Q1/68;A61K31/137 主分类号 A61K31/5513
代理机构 代理人
主权项 1. A method comprising: (a) receiving results of a test indicating that a patient comprises the minor allele of the single nucleotide polymorphism rs2237457; and (b) administering treatment to the patient for a psychiatric disorder.
地址 Evanston IL US