COMPOSITIONS AND METHODS FOR PREDICTION AND TREATMENT OF HUMAN CYTOMEGALOVIRUS INFECTIONS

摘要

The present invention relates to the field of virology. More specifically, the present invention provides compositions and methods useful for diagnosing and treating human cytomegalovirus. In one embodiment, a method for identifying a subject as susceptible to or likely to develop a human cytomegalovirus infection comprises the steps of (a) obtaining a biological sample from the subject; (b) performing an assay on the sample obtained from the subject to identify a mutation in NOD1 and/or NOD2; and (c) identifying the subject as susceptible to likely to develop human cytomegalovirus infection if the NOD1 and/or NOD2 mutation is identified.