发明名称 |
Method for preparation of the tetrasaccharide lacto-N-neotetraose (LNnt) containing N-acetyllactosamine |
摘要 |
The present invention relates to a method for preparation of the tetrasaccharide lacto-N-neotetraose (LNnt, formula (I)) especially in large scale, as well as intermediates in the synthesis, a new crystal form (polymorph) of LNnt, and the use thereof in pharmaceutical or nutritional compositions.; |
申请公布号 |
US8993740(B2) |
申请公布日期 |
2015.03.31 |
申请号 |
US201113579741 |
申请日期 |
2011.02.21 |
申请人 |
Glycom A/S |
发明人 |
Bajza István;Dekany Gyula;Ágoston Károly;Figuero-Pérez Ignacio;Boutet Julien;Hederos Markus;Horváth Ferenc;Kovács-Pénzes Piroska;Kröger Lars;Röhrig Christoph;Schroven Andreas;Vrasidas Ioannis;Trinka Péter;Kalmár László;Kovács Irme;Demkó Sándor;Ágoston Ágnes;Risinger Christian |
分类号 |
C07H15/04;C07H15/14;C07H15/203;C07H17/02;C07H13/04;A61K31/715;A61K31/7016;C08B37/00;C07H15/18;A23L1/09;A23L1/30;C07H11/00 |
主分类号 |
C07H15/04 |
代理机构 |
McHale & Slavin, P.A. |
代理人 |
McHale & Slavin, P.A. |
主权项 |
1. A polymorph of Galpβ1-4GlcNAcpβ1-3Galpβ1-4Glc (LNnT), characterized in that it displays X-ray powder diffraction reflections, based on a measurement using CuKα radiation, at 20.32±0.20, 19.10±0.20, 7.98±0.20, 21.03±0.20, 20.95±0.20 and 5.66±0.20 2Θ angles. |
地址 |
Kongens Lyngby DK |