发明名称 Method for preparation of the tetrasaccharide lacto-N-neotetraose (LNnt) containing N-acetyllactosamine
摘要 The present invention relates to a method for preparation of the tetrasaccharide lacto-N-neotetraose (LNnt, formula (I)) especially in large scale, as well as intermediates in the synthesis, a new crystal form (polymorph) of LNnt, and the use thereof in pharmaceutical or nutritional compositions.;
申请公布号 US8993740(B2) 申请公布日期 2015.03.31
申请号 US201113579741 申请日期 2011.02.21
申请人 Glycom A/S 发明人 Bajza István;Dekany Gyula;Ágoston Károly;Figuero-Pérez Ignacio;Boutet Julien;Hederos Markus;Horváth Ferenc;Kovács-Pénzes Piroska;Kröger Lars;Röhrig Christoph;Schroven Andreas;Vrasidas Ioannis;Trinka Péter;Kalmár László;Kovács Irme;Demkó Sándor;Ágoston Ágnes;Risinger Christian
分类号 C07H15/04;C07H15/14;C07H15/203;C07H17/02;C07H13/04;A61K31/715;A61K31/7016;C08B37/00;C07H15/18;A23L1/09;A23L1/30;C07H11/00 主分类号 C07H15/04
代理机构 McHale & Slavin, P.A. 代理人 McHale & Slavin, P.A.
主权项 1. A polymorph of Galpβ1-4GlcNAcpβ1-3Galpβ1-4Glc (LNnT), characterized in that it displays X-ray powder diffraction reflections, based on a measurement using CuKα radiation, at 20.32±0.20, 19.10±0.20, 7.98±0.20, 21.03±0.20, 20.95±0.20 and 5.66±0.20 2Θ angles.
地址 Kongens Lyngby DK