发明名称 |
MACROMOLECULES |
摘要 |
The present invention relates to a macromolecule comprising a dendrimer having surface amino groups to which at least two different terminal groups are attached including a pharmaceutically active agent and a pharmacokinetic modifying agent, the pharmaceutically active agent comprising a hydroxyl group and being attached to the surface amino group of the dendrimer through a diacid linker. Pharmaceutical compositions comprising the macromolecules and methods of treatment using the macromolecules are also described. |
申请公布号 |
EP2729179(A4) |
申请公布日期 |
2015.01.28 |
申请号 |
EP20120797060 |
申请日期 |
2012.06.06 |
申请人 |
STARPHARMA PTY LTD |
发明人 |
OWEN, DAVID;KELLY, BRIAN DEVLIN;KARELLAS, PETER |
分类号 |
A61K47/48;A61K31/00;A61K38/00;A61K39/00;A61K47/34;C08G73/02 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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